Celebrity weight-loss drugs may trigger dire side effect: doctor

A health care provider is warning that well-liked movie star fat-decline medicines like Ozempic and Wegovy could have a detrimental outcome on muscle mass.

Texas-based Dr. Peter Attia, who focuses on the science of longevity, claimed that he has observed people losing muscle mass at an alarming amount.

Wegovy and Ozempic — medicine that had been initially supposed to address people with Type 2 diabetes — make a human being feel fuller for for a longer time by slowing down digestion, which can direct to body weight loss.

Equally medication have a peptide identified as semaglutide, which mimics a hormone referred to as GLP-1 that is located naturally in your compact intestine.

In the course of Monday’s episode of his podcast, “The Peter Attia Generate,” he spoke at duration about the execs and downsides of the medicine, and reported that he believes the Food and Drug Administration doesn’t account for the style of bodyweight that persons missing in the several scientific tests on the injection — no matter whether it was muscle mass or fats.


Texas-based Dr. Peter Attia claims that men and women who take bodyweight-decline medications like Ozempic are losing muscle mass at an alarming charge.
Youtube / Peter Attia MD

He spoke about the effects of the drug at length during an episode of his podcast on Monday.
He spoke about the effects of the medicines throughout an episode of his podcast on Monday.
Youtube / Peter Attia MD

“So all of the studies that we’ve talked about, the Food and drug administration has forced the major consequence to be weight loss,” Dr. Attia mentioned in a clip of the podcast posted to his Instagram website page. “They do not care about human body composition.”

He employed the illustration of an individual who was 200 lbs and hypothetically shed 20 lbs . to illustrate his problems.

“There is not a solitary medical doctor out there really worth his or her salt that would say, ‘Well if that 20 lbs ., if 18 of that was muscle mass and two of that was excess fat, that would be a excellent matter,’” he discussed.

“Versus if 15 of that was excess fat, or 16 of that was extra fat, and 4 of it was muscle, those men and women both misplaced 20 pounds and they both of those missing 10% of their entire body bodyweight, but one of them decimated their lean entire body fat and the other had a dramatic improvement in body composition, and all those two are not the exact.”


The drug rose to popularity recently as it became approved for weight loss by the FDA.
The drug rose to reputation lately as it grew to become authorized for fat loss by the Fda.
AP

He warned against some of the side effects that come with using the drug Ozempic.
He warned against some of the facet consequences that come with making use of Ozempic.
AFP via Getty Photos

He also explained that several sufferers have been getting rid of muscle mass mass in an Instagram Reel that was posted in November.

“Almost without exception, every single patient we have place on this drug has dropped muscle mass mass,” he claimed in the video. “And they have misplaced it at a amount that alarms me.”

The health practitioner mentioned that whilst the drug is successful and appears to suppress hunger safely, it is not a “miracle drug,” which he even expanded on in a current weblog submit.

Dr. Attia declined additional comment to The Submit.


Comedian Chelsea Handler has admitted to taking the drug in the past.
Comedian Chelsea Handler has admitted to getting the drug in the past.
Getty Visuals for SXSW

In an emailed statement to The Publish, a representative for Novo Nordisk, the enterprise that manufactures Wegovy and Ozempic, wrote, “In clinical trials for Wegovy (semaglutide), we did not particularly review the medicine’s effect on muscle mass.”

Even so, they pointed to a single research, which was conducted as as element of the 1st stage in the drug’s enhancement, in which clients experienced loss in both fat and lean physique mass.

The producer acknowledged that while patients have lost muscle, they found that over-all, the clients studied had a increased proportion of muscle as opposed to their sum of fats.

“With regards to arm or leg weak spot, this is not a mentioned adverse response in our US full prescribing information and facts. We suggest that any individuals experiencing aspect outcomes even though taking Wegovy contact their healthcare supplier,” the company’s assertion claimed.


Elon Musk has also admitted to being on the drug.
Elon Musk has also admitted to having the drug.
Bloomberg by way of Getty Pictures

In modern months, the drug has appeared to just take in excess of Hollywood, as comic Chelsea Handler has copped to using it at just one position, as well as Elon Musk.

In the course of a Jan. 25 overall look on the “Simply call Her Daddy” podcast, Handler claimed that her physician palms out the drug to “anyone.”

“I arrived again from a trip and I injected myself with it. I went to lunch with a girlfriend a handful of times afterwards, and she was like, ‘I’m not seriously feeding on just about anything. I’m so nauseous, I’m on Ozempic,’” she claimed at the time.

Ozempic even designed an visual appeal at the 95th Annual Academy Awards, when late evening present host Jimmy Kimmel joked about it all through his opening monologue.

Kimmel chided, “When I search all around this area, I just cannot aid but question, is Ozempic ideal for me?”